Now showing items 1-2 of 2

    • Development of simplified heterocyclic acetogenin analogues as potent and selective Trypanosoma brucei inhibitors 

      Florence, Gordon J.; Fraser, Andrew L.; Gould, Eoin R.; King, Elizabeth F.; Menzies, Stefanie K.; Morris, Joanne C.; Thomson, Marie I.; Tulloch, Lindsay B.; Zacharova, Marija K.; Smith, Terry K. (2016-07-19) - Journal item
      Neglected tropical diseases caused by parasitic infections are an on-going and increasing concern and burden to human and animal health, having the most devastating effect on the world’s poorest countries. Building upon ...
    • Non-natural acetogenin analogues as potent Trypanosoma brucei inhibitors 

      Florence, Gordon J.; Fraser, Andrew L.; Gould, Eoin R.; King, Elizabeth F. B.; Menzies, Stefanie K.; Morris, Joanne C.; Tulloch, Lindsay B.; Smith, Terry K. (2014-11) - Journal article
      Neglected tropical diseases remain a serious global health concern. Here, a series of novel bis-tetrahydropyran 1,4-triazole analogues based on the framework of chamuvarinin, a polyketide natural product isolated from the ...