Now showing items 1-3 of 3

  • Isothiourea-catalysed acylative kinetic resolution of aryl-alkenyl (sp2 vs. sp2) substituted secondary alcohols 

    Musolino, Stefania F.; Ojo, O. Stephen; Westwood, Nicholas J.; Taylor, James E.; Smith, Andrew D. (2016-12-23) - Journal article
    The non-enzymatic acylative kinetic resolution of challenging aryl–alkenyl (sp2 vs. sp2) substituted secondary alcohols is described, with effective enantiodiscrimination achieved using the isothiourea organocatalyst ...
  • A scalable, chromatography-free synthesis of benzotetramisole 

    Daniels, David Sydney Bernard; Smith, Siobhan Rose; Lebl, Tomas; Shapland, P.; Smith, Andrew David (2015-01) - Journal article
    The scalable, chromatography-free synthesis of the chiral isothiourea benzotetramisole (BTM) in two steps from commercially available materials is presented. A detailed procedure for the synthesis of both enantiomers and ...
  • Three step synthesis of single diastereoisomers of the vicinal trifluoro motif 

    Brunet, Vincent A.; Slawin, Alexandra M. Z.; O'Hagan, David (2009-11-05) - Journal article
    A three step route to single diastereoisomers of the vicinal trifluoromethyl motif is described. The route starts from either syn- or anti-alpha,beta-epoxy alcohols and takes a direct approach in that each of the three ...