Now showing items 1-10 of 10

    • Antibodies for immunolabeling by light and electron microscopy : not for the faint hearted 

      Griffiths, Gareth; Lucocq, John Milton (2014-10) - Journal item
      Reliable antibodies represent crucial tools in the arsenal of the cell biologist and using them to localize antigens for immunocytochemistry is one of their most important applications. However, antibody-antigen interactions ...
    • Ardnamurchan 3D cone-sheet architecture explained by a single elongate magma chamber 

      Burchardt, Steffi; Troll, Valentin R.; Mathieu, Lucie; Emeleus, Henry C.; Donaldson, Colin Henry (2013-10-08) - Journal article
      The Palaeogene Ardnamurchan central igneous complex, NW Scotland, was a defining place for the development of the classic concepts of cone-sheet and ring-dyke emplacement and has thus fundamentally influenced our thinking ...
    • NMR Studies of Platinum bisphosphine complexes of phenylphosphonamidodiselenoate 

      Garland, Jaqueline; Cordes, David B.; Slawin, Alexandra M.Z.; Derek Woollins, J. (2015) - Journal article
      A series of platinum (II) bisphosphine complexes 1-20 [Pt(R’NH(Ph)PSe2)(PR3)2] (where R = Ph3, Ph2Me, Me2Ph, PMe3 and R’ = iPr, nBu, sBu, tBu, Benz) have been prepared by reaction of cis-[Pt(PR3)2Cl2)] and the alkyl ammonium ...
    • Observation-driven configuration of complex software systems 

      Sage, Aled (University of St Andrews, 2004-06) - Thesis
      The ever-increasing complexity of software systems makes them hard to comprehend, predict and tune due to emergent properties and non-deterministic behaviour. Complexity arises from the size of software systems and the ...
    • PCNA and XPF cooperate to distort DNA substrates 

      Hutton, Richard David; Craggs, Timothy David; White, Malcolm F; Penedo, Carlos (2010-03) - Journal article
      XPF is a structure-specific endonuclease that preferentially cleaves 3' DNA flaps during a variety of repair processes. The crystal structure of a crenarchaeal XPF protein bound to a DNA duplex yielded insights into how ...
    • Platinum bis(phosphine) complexes of 1,8-naphthosultam 

      Diamond, Louise M.; Knight, Fergus R.; Randall, Rebecca A. M.; Fuller, Amy L.; Slawin, Alexandra M. Z.; Woollins, J. Derek (2014-11-01) - Journal article
      A series of bis(phosphine) platinum complexes 1-4 and 6-8 that bear the 1,8-naphthosultam ligand (L) have been synthesised. The nitrogen atom in L was deprotonated with sodium tert-butoxide to form the sodium salt. ...
    • Platinum bisphosphine complexes of 1,8-naphthosultone 

      Diamond, Louise; Knight, Fergus Ross; Cordes, David B.; Fuller, Amy; Slawin, Alexandra Martha Zoya; Woollins, J Derek (2014-10-15) - Journal article
      A series of three platinum (II) bisphosphine complexes 1-3 [Pt(1-(SO2),8-(O)-nap)(PR3)2] (where R3 = Ph3, Ph2Me, Me2Ph) have been prepared by metathesis from cis-[Pt(PR3)2Cl2)] and the dilithium salt of 1,8-naphthosultone. ...
    • Preparation and organometallic complexes of the new unsymmetrical Ligand: Ph2PNHC6H4PPh2 

      Aucott, SM; Slawin, Alexandra Martha Zoya; Woollins, John Derek (1999-06-10) - Journal article
      Deprotonation of (2-diphenylphosphino)benzeneamine with BuLi followed by reaction with ClPPh2 in THF gave Ph2PNHC6H4PPh2 in good yields. The new unsymmetrical ligand has been incorporated into a number of complexes ...
    • Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing 

      Reeks, Judith; Sokolowski, Richard D.; Graham, Shirley; Liu, Huanting; Naismith, James H.; White, Malcolm F. (2013-06-01) - Journal article
      The competition between viruses and hosts is played out in all branches of life. Many prokaryotes have an adaptive immune system termed 'CRISPR' (clustered regularly interspaced short palindromic repeats) which is based ...
    • Synthesis and structural study of (8-phenylsulfanylnaphth-1-yl)diphenylphosphine metal complexes 

      Knight, Fergus R.; Fuller, Amy L.; Slawin, Alexandra M. Z.; Woollins, J. Derek (2010-05-27) - Journal article
      A series of three platinum(II) halide complexes 2-4 [Pt(X)(2)(Nap(PPh2)(SPh))] (Nap = naphthalene-1,8-diyl: X = Cl, Br, I) and a ruthenium(II) p-cymene complex 5 [Ru(eta(6)-(MeC6H4Pr)-Pr-i)(Cl){Nap(PPh2)(SPh)}]Cl-+(-) of ...