Now showing items 1-15 of 15

  • 2′-alkynylnucleotides : a sequence- and spin label-flexible strategy for EPR Spectroscopy in DNA 

    Haugland, Marius M.; El-Sagheer, Afaf H.; Porter, Rachel J.; Peña, Javier; Brown, Tom; Anderson, Edward A.; Lovett, Janet E. (2016-07-27) - Journal article
    Electron paramagnetic resonance (EPR) spectroscopy is a powerful method to elucidate molecular structure through the measurement of distances between conformationally well-defined spin labels. Here we report a sequence-flexible ...
  • Correction : Assessing dimerisation degree and cooperativity in a biomimetic small-molecule model by pulsed EPR 

    Ackermann, K.; Giannoulis, A.; Cordes, D. B.; Slawin, A. M. Z.; Bode, B. E. (2015-10-28) - Journal item
    Correction for ‘Assessing dimerisation degree and cooperativity in a biomimetic small-molecule model by pulsed EPR’ by K. Ackermann et al., Chem. Commun., 2015, 51, 5257–5260.
  • Design, synthesis and in vitro evaluation of indolotacrine analogues as multi-target-directed ligands for the treatment of Alzheimer’s disease 

    Benek, Ondrej; Soukup, Ondrej; Pasdiorova, Marketa; Hroch, Lukas; Sepsova, Vendula; Jost, Petr; Hrabinova, Martina; Jun, Daniel; Kuca, Kamil; Zala, Dominykas; Ramsay, Rona R.; Marco-Contelles, José; Musilek, Kamil (2016-06-20) - Journal article
    In this study, novel indolotacrine analogues have been designed, synthesized and evaluated as potential drugs for the treatment of Alzheimer’s disease. Based on a multi-target-directed ligand approach, novel compounds have ...
  • The electrophotonic silicon biosensor 

    Juan-Colás, José; Parkin, Alison; Dunn, Katherine E.; Scullion, Mark G.; Krauss, Thomas F.; Johnson, Steven D. (2016-09-14) - Journal article
    The emergence of personalized and stratified medicine requires label-free, low-cost diagnostic technology capable of monitoring multiple disease biomarkers in parallel. Silicon photonic biosensors combine high-sensitivity ...
  • An exhaustive symmetry approach to structure determination: phase transitions in Bi2Sn2O7 

    Lewis, James W.; Payne, Julia L.; Evans, Ivana Radosavljevic; Stokes, Harold T.; Campbell, Branton J.; Evans, John S. O. (2016-06-29) - Journal article
    The exploitable properties of many materials are intimately linked to symmetry-lowering structural phase transitions. We present an automated and exhaustive symmetry-mode method for systematically exploring and solving ...
  • High voltage Mg-doped Na0.67Ni0.3-xMgxMn0.7O2 (x = 0.05, 0.1) Na-ion cathodes with enhanced stability and rate capability 

    Singh, Gurpreet; Tapia-Ruiz, Nuria; Lopez Del Amo, Juan Miguel; Maitra, Urmimala; Somerville, James W.; Armstrong, A. Robert; Martinez de Ilarduya, Jaione; Rojo, Teófilo; Bruce, Peter G. (2016-07-26) - Journal article
    Magnesium substituted P2-structure Na0.67Ni0.3Mn0.7O2 materials have been prepared by a facile solid-state method and investigated as cathodes in sodium-ion batteries. The Mg-doped materials described here were characterized ...
  • Increasing the Brønsted acidity of Ph2PO2H by the Lewis acid B(C6F5)3. Formation of an eight-membered boraphosphinate ring [Ph2POB(C6F5)2O]2 

    Kather, Ralf; Rychagova, Elena; Camacho, Paula Sanz; Ashbrook, Sharon E.; Woollins, J. Derek; Robben, Lars; Lork, Enno; Ketkov, Sergey; Beckmann, Jens (2016-09-21) - Journal article
    Autoprotolysis of the metastable acid (C6F5)3BOPPh2OH, prepared in situ by the reaction of the rather weak Brønsted acid Ph2PO2H with the strong Lewis acid B(C6F5)3, gave rise to the formation of the eight-membered ring ...
  • Large thermoelectric power factors and impact of texturing on the thermal conductivity in polycrystalline SnSe 

    Popuri, S. R.; Pollet, M.; Decourt, R.; Morrison, Finlay; Bennett, N. S.; Bos, J. W. G. (2016-02-28) - Journal article
    Single crystals of SnSe have been reported to have very high thermoelectric efficiencies with a maximum figure merit zT = 2.5. This outstanding performance is due to ultralow thermal conductivities. We report on the synthesis ...
  • Living GenoChemetics by hyphenating synthetic biology and synthetic chemistry in vivo 

    Sharma, Sunil V.; Tong, Xiaoxue; Pubill-Ulldemolins, Cristina; Cartmell, Christopher; Bogosyan, Emma J. A.; Rackham, Emma J.; Marelli, Enrico; Hamed, Refaat B.; Goss, Rebecca J.M. (2017-08-09) - Journal article
    Marrying synthetic biology with synthetic chemistry provides a powerful approach toward natural product diversification, combining the best of both worlds: expediency and synthetic capability of biogenic pathways and ...
  • MIL-91(Ti), a small pore metal-organic framework which fulfils several criteria : an upscaled green synthesis, excellent water stability, high CO2 selectivity and fast CO2 transport 

    Benoit, Virginie; Pillai, Renjith S.; Orsi, Angelica; Normand, Périne; Jobic, Hervé; Nouar, Farid; Billemont, Pierre; Bloch, Emily; Bourrelly, Sandrine; Devic, Thomas; Wright, Paul A.; De Weireld, Guy; Serre, Christian; Maurin, Guillaume; Llewellyn, Philip L. (2016-01-28) - Journal article
    A multidisciplinary approach combining advanced experimental and modelling tools was undertaken to characterize the promises of a small-pore type Ti-based metal-organic framework, MIL-91(Ti) for CO2 capture. This material ...
  • Mutational signatures of ionizing radiation in second malignancies 

    Behjati, Sam; Gundem, Gunes; Wedge, David C.; Roberts, Nicola D.; Tarpey, Patrick S.; Cooke, Susanna L.; Van Loo, Peter; Alexandrov, Ludmil B.; Ramakrishna, Manasa; Davies, Helen; Nik-Zainal, Serena; Hardy, Claire; Latimer, Calli; Raine, Keiran M.; Stebbings, Lucy; Menzies, Andy; Jones, David; Shepherd, Rebecca; Butler, Adam P.; Teague, Jon W.; Jorgensen, Mette; Khatri, Bhavisha; Pillay, Nischalan; Shlien, Adam; Futreal, P. Andrew; Badie, Christophe; McDermott, Ultan; Bova, G. Steven; Richardson, Andrea L.; Flanagan, Adrienne M.; Stratton, Michael R.; Campbell, Peter J.; Lynch, Andrew G. (2016-09-12) - Journal article
    Ionizing radiation is a potent carcinogen, inducing cancer through DNA damage. The signatures of mutations arising in human tissues following in vivo exposure to ionizing radiation have not been documented. Here, we searched ...
  • Perfluorocarbon liquid under pressure : a medium for gas delivery 

    McKellar, Scott C.; Sotelo, Jorge; Mowat, John P S; Wright, Paul A.; Moggach, Stephen A. (2016-02-28) - Journal article
    A novel method for CO2 delivery to a porous material is reported, wherein a perfluorocarbon containing dissolved CO2 has been used as a pressure-transmitting liquid in a high-pressure single-crystal X-ray diffraction ...
  • A pulse of mid-Pleistocene rift volcanism in Ethiopia at the dawn of modern humans 

    Hutchison, William; Fusillo, Raffaella; Pyle, David M.; Mather, Tamsin A.; Blundy, Jon D.; Biggs, Juliet; Yirgu, Gezahegn; Cohen, Benjamin E.; Brooker, Richard A.; Barfod, Dan N.; Calvert, Andrew T. (2016-10-18) - Journal article
    The Ethiopian Rift Valley hosts the longest record of human co-existence with volcanoes on Earth, however, current understanding of the magnitude and timing of large explosive eruptions in this region is poor. Detailed ...
  • Quantum electric-dipole liquid on a triangular lattice 

    Shen, Shi-Peng; Wu, Jia-Chuan; Song, Jun-Da; Sun, Xue-Feng; Yang, Yi-Feng; Chai, Yi-Sheng; Shang, Da-Shan; Wang, Shou-Guo; Scott, James F.; Sun, Young (2016-02-04) - Journal article
    Geometric frustration and quantum fluctuations may prohibit the formation of long-range ordering even at the lowest temperature, and therefore liquid-like ground states could be expected. A good example is the quantum spin ...
  • Taking the pulse of Mars via dating of a plume-fed volcano 

    Cohen, Benjamin E.; Mark, Darren F.; Cassata, William S.; Lee, Martin R.; Tomkinson, Tim; Smith, Caroline L. (2017-12) - Journal article
    Mars hosts the solar system's largest volcanoes. Although their size and impact crater density indicate continued activity over billions of years, their formation rates are poorly understood. Here we quantify the growth ...