Now showing items 1-5 of 5

    • Artificial metalloenzymes : modified proteins as tuneable transition metal catalysts 

      Deuss, Peter J. (University of St Andrews, 2011-06-22) - Thesis
      This thesis describes the design, synthesis and application of artificial metalloenzymes for transition metal catalysed reactions not performed by natural enzymes. Unique cysteine containing protein templates were covalently ...
    • Artificial metalloenzymes in catalysis 

      Obrecht, Lorenz (University of St Andrews, 2015) - Thesis
      This thesis describes the synthesis, characterisation and application of artificial metalloenzymes as catalysts. The focus was on two mutants of SCP-2L (SCP-2L A100C and SCP-2L V83C) both of which possess a hydrophobic ...
    • Catalyst design in oxidation chemistry; from KMnO4 to artificial metalloenzymes 

      Doble, Megan; Ward, Andrew Christopher Clifford; Deuss, Peter; Jarvis, Amanda; Kamer, Paul C J (2014-10-15) - Journal article
      Oxidation reactions are an important part of the synthetic organic chemist’s toolkit and continued advancements have, in many cases, resulted in high yields and selectivities. This review aims to give an overview of the ...
    • Development of artificial metalloenzymes via covalent modification of proteins 

      Popa, Gina (University of St Andrews, 2010) - Thesis
      Development of selective artificial metalloenzymes by combining the biological concepts for selective recognition with those of transition metal catalysis has received much attention during the last decade. Targeting ...
    • Enzyme activity by design : an artificial rhodium hydroformylase for linear aldehydes 

      Jarvis, Amanda; Obrecht, Lorenz; Deuss, Peter; Laan, Wouter; Gibson, Emma K.; Wells, Peter P.; Kamer, Paul C J (2017-10-23) - Journal article
      Artificial metalloenzymes (ArMs) are hybrid catalysts that offer a unique opportunity to combine the superior performance of natural protein structures with the unnatural reactivity of transition-metal catalytic centers. ...