Now showing items 1-2 of 2

    • Simplifying nature : towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins 

      Gould, Eoin R.; King, Elizabeth F. B.; Menzies, Stefanie K.; Fraser, Andrew L.; Tulloch, Lindsay B.; Zacharova, Marija K.; Smith, Terry K.; Florence, Gordon J. (2017-11-15) - Journal article
      The need for new treatments for the neglected tropical diseases African sleeping sickness, Chagas disease and Leishmaniasis remains urgent with the diseases widespread in tropical regions, affecting the worlds very poorest. ...
    • The total synthesis of chamuvarinin 

      Morris, Joanne Charleen (University of St Andrews, 2013-11-29) - Thesis
      In 2004, the polyketide natural product, chamuvarinin (72) was isolated by Laurens et al. from the roots of Uvaria chamae, a member of the Annonaceae plant family. This unique tetrahydropyran containing acetogenin displayed ...