Now showing items 21-40 of 953

  • Accelerated degradation of MOFs under flue gas conditions 

    Mangano, Enzo; Kahr, Juergen; Wright, Paul; Brandani, Stefano (2016-04-20) - Journal article
    The zero length column (ZLC) technique is used to investigate the stability of Mg- and Ni-CPO-27 metal organic framework (MOF) crystals to the presence of water and humid flue gas. The design of the ZLC enables the stability ...
  • Accurate extraction of nanometer distances in multimers by pulse EPR 

    Valera, Silvia; Ackermann, Katrin; Pliotas, Christos; Huang, Hexian; Naismith, James Henderson; Bode, Bela Ernest (2016-03-24) - Journal article
    Pulse electron paramagnetic resonance (EPR) is gaining increasing importance in structural biology. The PELDOR (pulsed electron-electron double resonance) method allows extracting distance information on the nanometer ...
  • Accurate quantification of modified cyclic peptides without the need for authentic standards 

    Adaba, Rosemary I.; Mann, Greg; Raab, Andrea; Houssen, Wael E.; McEwan, Andrew R.; Thomas, Louise; Tabudravu, Jioji; Naismith, James H.; Jaspars, Marcel (2016-12-29) - Journal article
    There is a growing interest in the use of cyclic peptides as therapeutics, but their efficient production is often the bottleneck in taking them forward in the development pipeline. We have recently developed a method to ...
  • Acenaphtho[5,6-cd]-1,2-dichalcogenoles and their platinum complexes 

    Diamond, Louise; Knight, Fergus Ross; Cordes, David Bradford; Ward, Andrew Christopher Clifford; Slawin, Alexandra Martha Zoya; Woollins, J Derek (2015-01-08) - Journal article
    A related series of bis(phosphine) platinum complexes 1–5 and 6–8 bearing dichalcogenate acenaphthylene ligands have been synthesised. The chalcogen–chalcogen bonds in the parent acenaphtho[5,6-cd]-1,2-dichalcogenoles ...
  • Acetylation site specificities of lysine deacetylase inhibitors in human cells 

    Schölz, Christian; Weinert, Brian T.; Wagner, Sebastian A.; Beli, Petra; Miyake, Yasuyuki; Qi, Yun; Jensen, Lars J.; Streicher, Werner; McCarthy, Anna Rose; Westwood, Nicholas James; Lain, Sonya; Cox, Jürgen; Matthias, Patrick; Mann, Matthias; Bradner, James E.; Choudhary, Chunaram (2015) - Journal article
    Lysine deacetylases inhibitors (KDACIs) are used in basic research, and many are being investigated in clinical trials for treatment of cancer and other diseases. However, their specificities in cells are incompletely ...
  • Acetylene hydrogenation over structured Au-Pd catalysts 

    McCue, Alan J.; Baker, Richard; Anderson, James A. (2016-07-01) - Journal article
    AuPd nanoparticles were prepared following a methodology designed to produce core-shell structures (Au core and Pd shell). Characterisation suggested slow addition of the shell metal favoured deposition onto the pre-formed ...
  • The activation of Woollins' reagent. Isolation of pyridine stabilised PhPSe2 

    Ascherl, Laura; Nordheider, Andreas; Athukorala Arachchige, Kasun Sankalpa; Cordes, David Bradford; Karaghiosoff, Konstantin; Buehl, Michael; Slawin, Alexandra Martha Zoya; Woollins, J Derek (2014-06-14) - Journal article
    Woollins' reagent (WR, (PhPSe2)2) plays an essential role in the selenation of organic compounds. Reaction of WR with pyridine gives the P(V) species PhPSe2 stabilised by pyridine coordination which is the first ...
  • The ADOR mechanism for the synthesis of new zeolites 

    Eliášová, P.; Opanasenko, M.; Wheatley, Paul Stewart; Shamzhy, M.; Mazur, M.; Nachtigall, P.; Roth, W.J.; Morris, Russell Edward; Čejka, J. (2015-10-21) - Journal article
    A novel methodology, called ADOR (assembly-disassembly-organisation-reassembly), for the synthesis of zeolites is reviewed here in detail. The ADOR mechanism stems from the fact that certain chemical weakness against a ...
  • Adsorption materials and processes for carbon capture from gas-fired power plants : AMPGas 

    Gibson, J. A. Arran; Mangano, Enzo; Shiko, Elenica; Greenaway, Alex; Gromov, Andrei V.; Lozinska, Magdalena M.; Friedrich, Daniel; Campbell, Eleanor E. B.; Wright, Paul A.; Brandani, Stefano (2016-04-06) - Journal article
    The key challenge in postcombustion capture from gas-fired power plants is related to the low CO2 concentration in the flue gas (4–8% by volume). This means that conventional amine processes will result in a relatively ...
  • Adsorption of a dihydro-TTF derivative on Au(111) via a thiolate bonding complex to gold adatoms 

    Jethwa, Siddharth Janak; Grillo, Federico; Fruchtl, Herbert Anton; Simpson, Grant James; Treanor, Michael John; Schaub, Renald; Francis, Stephen Malcolm; Richardson, Neville V; Aitken, R Alan (2014-08-05) - Journal article
    A dihydro-TTF derivative with four acetyl-protected thiol ligands was synthesised and adsorbed on Au(111) under UHV conditions. Scanning Tunnelling Microscopy (STM) and Infrared (IR) spectroscopy show that self-organised ...
  • Advanced model compounds for understanding acid catalyzed lignin depolymerization: identification of renewable aromatics and a lignin-derived solvent 

    Lahive, Ciaran; Deuss, Peter J.; Lancefield, Christopher Stuart; Sun, Zhuohua; Cordes, David B.; Young, Claire M.; Tran, Fanny; Slawin, Alexandra M. Z.; de Vries, Johannes G.; Kamer, Paul C. J.; Westwood, Nicholas J.; Barta, Katalin (2016-07-20) - Journal article
    The development of fundamentally new approaches for lignin depolymerization is challenged by the complexity of this aromatic biopolymer. While overly simplified model compounds often lack relevance to the chemistry of ...
  • The AEROPATH project targeting Pseudomonas aeruginosa : crystallographic studies for assessment of potential targets in early-stage drug discovery 

    Moynie, Lucile; Schnell, Robert; McMahon, Stephen A.; Sandalova, Tatyana; Abdelli Boulkeroua, Wassila; Schmidberger, Jason W.; Alphey, Magnus; Cukier, Cyprian; Duthie, Fraser; Kopec, Jolanta; Liu, Huanting; Jacewicz, Agata; Hunter, William N.; Naismith, James H.; Schneider, Gunter (2013-01) - Journal article
    Bacterial infections are increasingly difficult to treat owing to the spread of antibiotic resistance. A major concern is Gram-negative bacteria, for which the discovery of new antimicrobial drugs has been particularly ...
  • Air exposure induced recombination in PTB7:PC71BM solar cells 

    Thomson, Stuart A. J.; Hogg, Stephen C.; Samuel, Ifor D. W.; Keeble, David J. (2017-11-07) - Journal article
    Understanding degradation pathways in organic photovoltaic cells (OPV) is essential to achieve long term device stability and allow commercialisation. Upon exposure to an ambient atmosphere the power conversion efficiency ...
  • ALDH2 mediates 5-nitrofuran activity in multiple species 

    Zhou, Linna; Ishizaki, Hironori; Spitzer, Michaela; Taylor, Kerrie; Temperley, Nicholas; Johnson, Stephen; Brear, Paul; Gautier, Philippe; Zeng, Zhiqiang; Mitchell, Amy; Narayan, Vikram; McNeil, Ewan; Melton, David; Smith, Terry K; Tyers, Mike; Westwood, Nicholas James; Patton, Elizabeth (2012-07-27) - Journal article
    Understanding how drugs work in vivo is critical for drug design and for maximizing the potential of currently available drugs. 5-nitrofurans are a class of pro-drugs widely used to treat bacterial and trypanosome infections, ...
  • All-cis 1,2,3,4,5,6-hexafluorocyclohexane is a facially polarised cyclohexane 

    Keddie, Neil Steven; Slawin, Alexandra Martha Zoya; Lebl, Tomas; Philp, Douglas; O'Hagan, David (2015-04) - Journal article
    The highest-energy stereoisomer of 1,2,3,4,5,6-hexafluorocyclohexane, in which all of the fluorines are ‘up’, is prepared in a 12-step protocol. The molecule adopts a classic chair conformation with alternate C–F bonds ...
  • alpha-Ketophosphonates as ester surrogates : isothiourea-catalyzed asymmetric diester and lactone synthesis 

    Smith, Siobhan R.; Leckie, Stuart M.; Holmes, Reuben; Douglas, James; Fallan, Charlene; Shapland, Peter; Pryde, David; Slawin, Alexandra M. Z.; Smith, Andrew D. (2014-05-02) - Journal article
    Isothiourea HBTM-2.1 catalyzes the asymmetric Michael addition/lactonization of aryl- and alkenylacetic acids using α-keto-β,γ-unsaturated phosphonates as α,β-unsaturated ester surrogates, giving access to a diverse range ...
  • Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli 

    Lou, Hubing; Chen, Min; Black, Susan S.; Bushell, Simon R.; Ceccarelli, Matteo; Mach, Tivadar; Beis, Konstantinos; Low, Alison S.; Bamford, Victoria A.; Booth, Ian R.; Bayley, Hagan; Naismith, James H. (2011-10-28) - Journal article
    Antibiotic-resistant bacteria, particularly Gram negative species, present significant health care challenges. The permeation of antibiotics through the outer membrane is largely effected by the porin superfamily, changes ...
  • Alternative hydrogen peroxide sources for peroxyoxalate “glowstick” chemiluminescence demonstrations 

    Smellie, Iain A.; Aldred (née Prentis), Joanna K. D.; Bower, Benjamin; Cochrane, Amber; Macfarlane, Laurie; McCarron, Hollie B.; O'Hara, Roxanna; Patterson, Iain L. J.; Thomson, Marie I.; Walker, Jessica M. (2017-01-10) - Journal article
    Simple protocols have been devised for peroxyoxalate chemiluminescence demonstrations that use urea–hydrogen peroxide or sodium percarbonate as oxidants in place of aqueous solutions of hydrogen peroxide. The procedures ...
  • The ambient hydration of the aluminophosphate JDF-2 to AlPO-53(A) : insights from NMR crystallography 

    Dawson, Daniel M.; Walton, Richard I.; Wimperis, Stephen; Ashbrook, Sharon E. (2017-02-06) - Journal article
    The aluminophosphate (AlPO), JDF-2 is prepared hydrothermally with methylammonium hydroxide (MAH+ HO–, MAH+ = CH3NH3+), giving rise to a microporous AEN-type framework with occluded MAH+ and extra framework (Al-bound) HO–. ...
  • Ammonium Phenylphosphonamidodiselenoates and Phenylphosphonamidodi-selenoic Diamides from the Selenation of Primary and Secondary Amines 

    Hua, Guoxiong; Randall, Rebecca A. M.; Slawin, Alexandra M. Z.; Woollins, J. Derek (2011-10) - Journal article
    By reacting two equivalents of primary or secondary amines with 2,4-bis(phenyl)-1,3-diselenadiphosphetane-2,4-diselenide (Woollins' reagent) at room temperature a series of new ammonium phenylphosphonamidodiselenoates 1-7 ...