Now showing items 1-4 of 4

  • Impact of interferon β and interferon stimulated gene induction on Bunyamwera virus replication 

    Carlton-Smith, Charles (University of St Andrews, 2012-06-20) - Thesis
    The first line of defence against viral infection is the interferon (IFN) response, which must be overcome by a virus for successful replication. Pattern recognition receptors detect virus which triggers induction of IFNβ. ...
  • Influenza A viruses and PI3K signalling 

    Hale, Benjamin G. (University of St Andrews, 2007-09-28) - Thesis
    The influenza A virus non-structural (NS1) protein is multifunctional, and during virus-infection NS1 interacts with several factors in order to manipulate host-cell processes. This study reports that NS1 binds directly ...
  • Molecular biology of giant viruses' DNA replication machinery 

    Evripioti, Antonia Alexandra (University of St Andrews, 2013-11) - Thesis
    Viruses are the most widespread and abundant entity on this planet, further constituting the largest part of the genosphere. The majority of these infectious agents are miniature, having been described as being smaller ...
  • Studies on influenza A virus PB1-F2 protein 

    Vater, Sandra (University of St Andrews, 2011-11-30) - Thesis
    The influenza A virus genome codes for up to 12 proteins. Segment 2 encodes three proteins, the polymerase subunit PB1, a small protein PB1-F2 and an N-terminally truncated version of PB1 called N40. Different functions ...