Now showing items 1-3 of 3

  • Functional analysis of Leishmania cyclopropane fatty acid synthetase 

    Oyola, Samuel O.; Evans, Krystal J.; Smith, Terry K.; Smith, Barbara A.; Hilley, James D.; Mottram, Jeremy C.; Kaye, Paul M.; Smith, Deborah F. (2012-12-10) - Journal article
    The single gene encoding cyclopropane fatty acid synthetase (CFAS) is present in Leishmania infantum, L. mexicana and L. braziliensis but absent from L. major, a causative agent of cutaneous leishmaniasis. In L. infantum, ...
  • Phospholipases A1 

    Richmond, Gregory S.; Smith, Terry K. (2011-01) - Journal item
    Phospholipase A1 (PLA1) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse ...
  • Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase 

    Sgraja, Tanja; Smith, Terry K; Hunter, William N. (2007-03-30) - Journal article
    Background: Isoprenoid precursor synthesis via the mevalonate route in humans and pathogenic trypanosomatids is an important metabolic pathway. There is however, only limited information available on the structure and ...