Now showing items 1-3 of 3

  • PCNA and XPF cooperate to distort DNA substrates 

    Hutton, Richard David; Craggs, Timothy David; White, Malcolm F; Penedo, Carlos (2010-03) - Journal article
    XPF is a structure-specific endonuclease that preferentially cleaves 3' DNA flaps during a variety of repair processes. The crystal structure of a crenarchaeal XPF protein bound to a DNA duplex yielded insights into how ...
  • A transient homotypic interaction model for the influenza A virus NS1 protein effector domain 

    Kerry, Philip S.; Ayllon, Juan; Taylor, Margaret A.; Hass, Claudia; Lewis, Andrew; Garcia-Sastre, Adolfo; Randall, Richard E.; Hale, Benjamin G.; Russell, Rupert J. (2011-03-28) - Journal article
    Influenza A virus NS1 protein is a multifunctional virulence factor consisting of an RNA binding domain (RBD), a short linker, an effector domain (ED), and a C-terminal 'tail'. Although poorly understood, NS1 multimerization ...
  • Wzi Is an Outer Membrane Lectin that Underpins Group 1 Capsule Assembly in Escherichia coli 

    Bushell, Simon; Mainprize, Iain L.; Wear, Martin A.; Lou, Hubing; Whitfield, Chris; Naismith, Jim (2013-04-25) - Journal article
    Many pathogenic bacteria encase themselves in a polysaccharide capsule that provides a barrier to the physical and immunological challenges of the host. The mechanism by which the capsule assembles around the bacterial ...