Browsing by Subject "QH301 Biology"
Now showing items 1-20 of 1077
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1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders
(2018) - Journal articleSeveral neurodegenerative disorders including Alzheimer’s disease (AD) have been connected with deregulation of casein kinase 1 (CK1) activity. Inhibition of CK1 therefore presents a potential therapeutic strategy against ... -
16S rRNA gene metabarcoding and TEM reveals different ecological strategies within the genus Neogloboquadrina (planktonic foraminifer)
(2018-01-29) - Journal articleUncovering the complexities of trophic and metabolic interactions among microorganisms is essential for the understanding of marine biogeochemical cycling and modelling climate-driven ecosystem shifts. High-throughput DNA ... -
17ß-Estradiol protects against the effects of a high fat diet on cardiac glucose, lipid and nitric oxide metabolism in rats
(2017-05-05) - Journal articleThe aim of this study was to investigate the in vivo effects of estradiol (E2) on myocardial metabolism and inducible nitric oxide synthase (iNOS) expression/activity in obese rats. Male Wistar rats were fed with a normal ... -
2A - the "go-to" technology for transgene co-expression
(2015-08-26) - Journal itemIn order to co-express multiple genes for biotechnological and biomedical applications, several approaches have been used with varying degrees of success. Currently, internal ribosome entry site (IRES) elements and ... -
"2A-like" signal sequences mediating translational recoding : a novel form of dual protein targeting
(2016-08) - Journal articleWe report the initial characterisation of an N-terminal oligopeptide ‘2A-like’ sequence that is able to function both as a signal sequence and as a translational recoding element. Due to this translational recoding activity, ... -
3D camouflage : exploiting photons to conceal form
(2015-10) - Journal articleMany animals have a gradation of body color, termed countershading, where the areas that are typically exposed to more light are darker. One hypothesis is that this patterning enhances visual camouflage by making the retinal ... -
A 3D stereo camera system for precisely positioning animals in space and time
(2015-04) - Journal articleHere, we describe a portable stereo camera system that integrates a GPS receiver, an attitude sensor and 3D stereo photogrammetry to rapidly estimate the position of multiple animals in space and time. We demonstrate the ... -
4273π : bioinformatics education on low cost ARM hardware
(2013-08-12) - Journal articleBackground: Teaching bioinformatics at universities is complicated by typical computer classroom settings. As well as running software locally and online, students should gain experience of systems administration. For a ... -
5-hydroxymethylcytosine marks promoters in colon that resist DNA hypermethylation in cancer
(2015-04-01) - Journal articleBackground : The discovery of cytosine hydroxymethylation (5hmC) as a mechanism that potentially controls DNA methylation changes typical of neoplasia prompted us to investigate its behaviour in colon cancer. 5hmC is ... -
Absolute abundance estimates from shallow water baited underwater camera surveys; a stochastic modelling approach tested against field data
(2015-11) - Journal articleBaited underwater cameras are becoming a popular tool to monitor fish and invertebrate populations within protected and inshore environments where trawl surveys are unsuitable. Modelling the arrival times of deep-sea ... -
Abundance and distribution of sperm whales in the Canary Islands : can sperm whales in the Archipelago sustain the current level of ship-strike mortalities?
(2016-03-21) - Journal articleSperm whales are present in the Canary Islands year-round, suggesting that the archipelago is an important area for this species in the North Atlantic. However, the area experiences one of the highest reported rates of ... -
The ACER pollen and charcoal database : a global resource to document vegetation and fire response to abrupt climate changes during the last glacial period
(2017-09-11) - Journal articleQuaternary records provide an opportunity to examine the nature of the vegetation and fire responses to rapid past climate changes comparable in velocity and magnitude to those expected in the 21st-century. The best ... -
Acoustic and foraging behavior of a Baird’s beaked whale, Berardius bairdii, exposed to simulated sonar
(2014-11-13) - Journal articleBeaked whales are hypothesized to be particularly sensitive to anthropogenic noise, based on previous strandings and limited experimental and observational data. However, few species have been studied in detail. We describe ... -
Acoustic communication in insect disease vectors
(2013-12) - Journal articleAcoustic signalling has been extensively studied in insect species, which has led to a better understanding of sexual communication, sexual selection and modes of speciation. The significance of acoustic signals for a ... -
Acoustic sequences in non-human animals : a tutorial review and prospectus
(2016-02) - Journal articleAnimal acoustic communication often takes the form of complex sequences, made up of multiple distinct acoustic units. Apart from the well-known example of birdsong, other animals such as insects, amphibians,and mammals ... -
Activity profiles and hook-tool use of New Caledonian crows recorded by bird-borne video cameras
(2015-12-23) - Journal articleNew Caledonian crows are renowned for their unusually sophisticated tool behaviour. Despite decades of fieldwork, however, very little is known about how they make and use their foraging tools in the wild, which is largely ... -
Adaptation to a seasonally varying environment : a strong latitudinal cline in reproductive diapause combined with high gene flow in Drosophila montana
(2011-10) - Journal articleAdaptation to seasonal changes in the northern hemisphere includes an ability to predict the forthcoming cold season from gradual changes in environmental cues early enough to prepare for the harsh winter conditions. The ... -
Adapting a computational multi agent model for humpback whale song research for use as a tool for algorithmic composition
(Hochschule für Musik und Theater Hamburg, 2016-08-31) - Conference itemHumpback whales (Megaptera Novaengliae) present one of the most complex displays of cultural transmission amongst non-humans. During breeding seasons, male humpback whales create long, hierarchical songs, which are shared ... -
Adapting to a warmer ocean – seasonal shift of baleen whale movements over three decades
(2015-03-18) - Journal articleGlobal warming poses particular challenges to migratory species, which face changes to the multiple environments occupied during migration. For many species, the timing of migration between summer and winter grounds and ... -
Adaptive sequence evolution is driven by biotic stress in a pair of orchid species (Dactylorhiza) with distinct ecological optima
(2017-07-04) - Journal articleThe orchid family is the largest in the angiosperms, but little is known about the molecular basis of the significant variation they exhibit. We investigate here the transcriptomic divergence between two European terrestrial ...