Now showing items 1-20 of 1069

  • 1,1'-Diethyl-4,4'-bipyridine-1,1'-diium bis(1,1,3,3-tetracyano-2- ethoxypropenide) : multiple C-H⋯N hydrogen bonds form a complex sheet structure 

    Setifi, Z.; Lehchili, F.; Setifi, F.; Beghidja, A.; Ng, S.W.; Glidewell, C. (2014-03-01) - Journal article
    In the title salt, C14H18N22+·2C9H5N4O−, the 1,1′-diethyl-4,4′-bipyridine-1,1′-diium dication lies across a centre of inversion in the space group P21/c. In the 1,1,3,3-tetracyano-2-ethoxypropenide anion, the two independent ...
  • 1,2,5-Selenadiazolo[3,4-b]pyrazines : synthesis from 3,4-Diamino-1,2,5-selenadiazole and Generation of Persistent Radical Anions 

    Konstantinova, Lidia S.; Bobkova, Irina E.; Nelyubina, Yulia V.; Chulanova, Elena A.; Irtegova, Irina G.; Vasilieva, Nadezhda V.; Sanz Camacho, Paula; Ashbrook, Sharon Elizabeth Marie; Hua, Guoxiong; Slawin, Alexandra Martha Zoya; Woollins, J Derek; Zibarev, Andrey V.; Rakitin, Oleg A. (2015-09) - Journal article
    Synthesis of 3,4-disubstituted and fused 1,2,5-selenadiazolo[3,4-b]pyrazines via previously unknown 3,4-diamino-1,2,5-selenadiazole has been achieved in moderate to high yields. The compounds synthesized were characterized ...
  • 1,2-Bis(2-bromobenzyl)diselane 

    Hua, Guoxiong; Fuller, Amy L.; Slawin, Alexandra M. Z.; Woollins, J. Derek (2010-10) - Journal article
    In the title compound, C14H12Br2Se2, the Se-Se bond length [2.3034 (9) angstrom] is similar to those in diphenyl diselenide [2.3066 (7) and 2.3073 (10) angstrom] and shorter than that in 1,8-diselenonaphthalene [2.0879 (8) ...
  • 1,4-Oxazine 

    Aitken, R Alan; Aitken, Kati Marianne; Carruthers, Phillip G; Jean, Marc-Alexandre; Slawin, Alexandra Martha Zoya (2013) - Journal article
    The fundamental heterocyclic compound 1,4-oxazine has been generated using FVP. It is the first parent heterocycle among all the possible isomeric oxazines, thiazines and their heavier atom analogues to be characterised ...
  • 1,5,6-Triphenyl-8-oxa-7-selena-6-phosphabicyclo[3.2.1]octane-6-selone 

    Hua, Guoxiong; Li, Yang; Slawin, Alexandra Martha Zoya; Woollins, J Derek (2008-01) - Journal article
    The structure of the title compound, C23H21OPSe2, consists of fused puckered five- and six-membered rings, PSeC2O and C5O, respectively, with a C2O bridgehead. The C5O ring adopts a chair conformation, whilst the C2PSeO ...
  • 1-(3-Phenylpropyl)urea 

    Li, Yang; Hua, Guoxiong; Slawin, Alexandra M. Z.; Woollins, J. Derek (2009-10) - Journal article
    In the crystal of the title compound, C10H14N2O, double supramolecular layers of PhCH2CH2CH2NHC(O)NH2 are formed parallel to the bc plane by intermolecular N-H center dot center dot center dot O hydrogen bonding, with ...
  • 1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders 

    Benek, Ondrej; Hroch, Lukas; Aitken, Laura; Gunn-Moore, Frank; Vinklarova, Lucie; Kuca, Kamil; Perez, Daniel I.; Perez, Concepcion; Martinez, Ana; Fisar, Zdenek; Musilek, Kamil (2018) - Journal article
    Several neurodegenerative disorders including Alzheimer’s disease (AD) have been connected with deregulation of casein kinase 1 (CK1) activity. Inhibition of CK1 therefore presents a potential therapeutic strategy against ...
  • 17O solid-state NMR spectroscopy of A2B2O7 oxides : quantitative isotopic enrichment and spectral acquisition? 

    Fernandes, Arantxa; Moran, Robert; Sneddon, Scott; Dawson, Daniel M.; McKay, David; Bignami, Giulia P. M.; Blanc, Frédéric; Whittle, Karl; Ashbrook, Sharon E. (2018-02-14) - Journal article
    The potential of 17O NMR spectroscopy for the investigation of A2B2O7 ceramic oxides important in the encapsulation of radioactive waste, is demonstrated, with post-synthetic enrichment by exchange with 17O2 gas. For ...
  • 2,2 '-o-Phenylenediacetonitrile 

    Li, Yang; Hua, Guoxiong; Slawin, Alexandra M. Z.; Woollins, J. Derek (2009-11) - Journal article
    In the title compound, NCCH2C6H4CH2CN, the bond lengths and angles are within normal ranges. The benzene ring makes dihedral angles of 4.94 (8) and 77.04 (8)degrees with the C-C-C-N mean planes. Weak non-conventional C-H ...
  • 2,4,5-Triphenyl-1,3,2-dioxaphospholan-2-one 

    Cordes, David B.; Hua, Guoxiong; Slawin, Alexandra M. Z.; Woollins, J. Derek (2011-07) - Journal article
    The dioxaphospholane ring in the title compound, C20H17O3P, adopts an envelope conformation about one of the ring carbons. The benzene rings of the compound do not form face-to-face pi-pi interactions, instead weak C-H ...
  • 2-(4-Fluorophenyl)-3-methyl-1H-indole 

    Cordes, David B.; Hua, Guoxiong; Slawin, Alexandra M. Z.; Woollins, J. Derek (2011-07) - Journal article
    The indole N-H hydrogen in the title compound, C15H12FN, does not display classical hydrogen bonding. Rather it forms an interaction with the pi system of an adjacent indole, resulting in weakly interacting chains along ...
  • 2-Arylacetic anhydrides as ammonium enolate precursors 

    Morrill, Louis C.; Ledingham, Lyndsay A.; Couturier, Jean-Philippe; Bickel, Jasmine; Harper, Andrew D.; Fallan, Charlene; Smith, Andrew D. (2014-01-28) - Journal article
    Readily prepared 2-arylacetic anhydrides act as convenient ammonium enolate precursors in isothiourea (HBTM-2.1)-mediated catalytic asymmetric intermolecular Michael addition-lactonisation processes, giving diverse synthetic ...
  • 2-Phenyl-5-(p-tolyl)-1,3,4-oxadiazole 

    Cordes, David B.; Hua, Guoxiong; Slawin, Alexandra M. Z.; Woollins, J. Derek (2011-07) - Journal article
    The title compound, C15H12N2O, adopts the expected near-planar geometry, the phenyl and tolyl rings being inclined relative to the oxadiazole ring by 3.8 (3) and 8.3 (2)degrees, respectively. This allows adjacent molecules ...
  • 2′-alkynylnucleotides : a sequence- and spin label-flexible strategy for EPR Spectroscopy in DNA 

    Haugland, Marius M.; El-Sagheer, Afaf H.; Porter, Rachel J.; Peña, Javier; Brown, Tom; Anderson, Edward A.; Lovett, Janet E. (2016-07-27) - Journal article
    Electron paramagnetic resonance (EPR) spectroscopy is a powerful method to elucidate molecular structure through the measurement of distances between conformationally well-defined spin labels. Here we report a sequence-flexible ...
  • 3-2: Invited paper: Color on Demand - Color-tunable OLEDs for lighting and displays 

    Fröbel, Markus; Schwab, Tobias; Kliem, Mona; Lenk, Simone; Leo, Karl; Reineke, Sebastian; Gather, Malte C. (2017-05) - Journal article
    A device concept for highly efficient OLEDs is introduced that allows to tune the emission color of the device over a broad range of the CIE color gamut. The approach exploits the different polarities of the positive and ...
  • 5-Amino-3-methyl-1,2,4-thiadiazole 

    Aitken, R. Alan; Slawin, Alexandra M. Z. (2018-01-21) - Journal article
    An improved procedure for isolation of 5-amino-3-methyl-1,2,4-thiadiazole in pure form on a multi-gram scale without chromatography is reported. Its 1H and 13C NMR and IR data are presented and previously published erroneous ...
  • 50-1: Invited paper: Recent advances in measuring and understanding the influence of molecular alignment on the light extraction efficiency of OLEDs 

    Murawski, Caroline; Graf, Arko; Liehm, Philipp; Neferu, Ana; Zysman-colman, Eli; Gather, Malte C. (2017-05) - Journal item
    We review recent progress in controlling the alignment of the transition dipole moment of electroluminescent molecules to maximize the light extraction efficiency in OLEDs. Particular focus devoted to ways of measuring ...
  • (5RS)-5-(4-Methoxyphenyl)-2-(methylsulfanyl)benzo[g]pyrimido[4,5-b]quinoline-4,6,11(3H,5H,12H)-trione, with Z '=3, forms a three-dimensional hydrogen-bonded framework containing five types of hydrogen bond 

    Castillo, Yelder A.; Zapata, Luis F.; Trilleras, Jorge; Cobo, Justo; Glidewell, Christopher (2014-01) - Journal article
    The title compound, C23H17N3O4S, crystallizes with Z' = 3 in the space group P. Two of the three independent molecules are broadly similar in terms of both their molecular conformations and their participation in hydrogen ...
  • 6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment : design, synthesis and in vitro evaluation 

    Benek, Ondrej; Hroch, Lukas; Aitken, Laura; Dolezal, Rafael; Guest, Patrick; Benkova, Marketa; Soukup, Ondrej; Musil, Karel; Hughes, Rebecca; Kuca, Kamil; Smith, Terry K.; Gunn-Moore, Frank; Musilek, Kamil (2017-06) - Journal article
    Background : The mitochondrial enzyme amyloid beta-binding alcohol dehydrogenase (ABAD) also known as 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) has been connected with the pathogenesis of Alzheimer’s disease ...
  • 6-exo-trig Michael addition-lactonizations for catalytic enantioselective chromenone synthesis 

    N P, Rifahath Mon; Cordes, David Bradford; Slawin, Alexandra Martha Zoya; Smith, Andrew David (2017-02-28) - Journal article
    The catalytic enantioselective 6-exo-trig Michael addition-lactonization of enone-acid substrates to form cis-chromenones with high diastereo- and enantiocontrol was developed using the commercially available isothiourea ...