Now showing items 1-7 of 7

  • Catalyst design in oxidation chemistry; from KMnO4 to artificial metalloenzymes 

    Doble, Megan; Ward, Andrew Christopher Clifford; Deuss, Peter; Jarvis, Amanda; Kamer, Paul C J (2014-10-15) - Journal article
    Oxidation reactions are an important part of the synthetic organic chemist’s toolkit and continued advancements have, in many cases, resulted in high yields and selectivities. This review aims to give an overview of the ...
  • A new class of NO-donor pro-drugs triggered by γ-glutamyl transpeptidase with potential for reno-selective vasodilatation 

    Zhang, Qingzhi; Kulczynska, Agnieszka; Webb, David J.; Megson, Ian L.; Botting, Nigel P. (2013) - Journal article
    This communication describes the synthesis of a new class of N-hydroxyguanidine (NHG) pro-drugs which release nitric oxide (NO), triggered by the action of gamma-glutamyl transpeptidase (gamma-GT), and have potential for ...
  • Planar P6E6 (E = Se, S) macrocycles incorporating P2N2 scaffolds 

    Nordheider, Andreas; Chivers, Tristram; Thirumoorthi, Ramalingam; Vargas-Baca, Ignacio; Woollins, J. Derek (2012-05) - Journal article
    Oxidation of alkali metal derivatives of the dianions [E((BuN)-Bu-t)P(mu-(NBu)-Bu-t)(2)P((NBu)-Bu-t)E](2-) (E = S, Se) with I-2 produces 15-membered macrocycles in which a planar P6E6 motif is stabilised by perpendicular ...
  • The respiratory arsenite oxidase : structure and the role of residues surrounding the rieske cluster 

    Warelow, Thomas P.; Oke, Muse; Schoepp-Cothenet, Barbara; Dahl, Jan U.; Bruselat, Nicole; Sivalingam, Ganesh N.; Leimkuehler, Silke; Thalassinos, Konstantinos; Kappler, Ulrike; Naismith, James H.; Santini, Joanne M. (2013-08-30) - Journal article
    The arsenite oxidase (Aio) from the facultative autotrophic Alphaproteobacterium Rhizobium sp. NT-26 is a bioenergetic enzyme involved in the oxidation of arsenite to arsenate. The enzyme from the distantly related ...
  • Sterically crowded peri-substituted naphthalene phosphines and their PV derivatives 

    Knight, Fergus Ross; Fuller, Amy; Buehl, Michael; Slawin, Alexandra Martha Zoya; Woollins, J Derek (2010-07-05) - Journal article
    Three sterically crowded peri-substituted naphthalene phosphines, Nap[PPh2][ER] (Nap=naphthalene-1,8-diyl; ER=SEt, SPh, SePh) 1–3 , which contain phosphorus and chalcogen functional groups at the peri positions have been ...
  • Towards the development of selective hydrocarbon oxygenation catalysts 

    Guisado Barrios, Gregorio (University of St Andrews, 2010-03-09) - Thesis
    The synthesis of pure tris(6-hydroxymethyl-2-pyridylmethyl)amine (H₃L₁₁) is reported for the first time. New complexes of H₃L₁₁ with copper(II), manganese(II) and iron(III) have been characterised by X-ray crystallography. ...
  • Using molecular oxygen in synthesis : applications in lignin valorisation and natural product synthesis 

    Lancefield, Christopher Stuart (University of St Andrews, 2015-06-24) - Thesis
    The first part of this thesis describes my research towards the valorisation of lignin. Due to environmental and political pressures, there has been a drive to start the transition from a fossil fuel based economy to a ...