Now showing items 1-12 of 12

  • Applications of microfluidic chips in optical manipulation & photoporation 

    Marchington, Robert F. (University of St Andrews, 2010-10-01) - Thesis
    Integration and miniaturisation in electronics has undoubtedly revolutionised the modern world. In biotechnology, emerging lab-on-a-chip (LOC) methodologies promise all-integrated laboratory processes, to perform complete ...
  • Applications of microfluidics and optical manipulation for photoporation and imaging 

    Rendall, Helen A. (University of St Andrews, 2015-06-24) - Thesis
    Optical manipulation covers a wide range of techniques to guide and trap cells using only the forces exerted by light. Another optical tool is photoporation, the technique of injecting membrane-impermeable molecules using ...
  • Creating and probing of a perfect vortex in situ with an optically trapped particle 

    Chen, Mingzhou; Mazilu, Michael; Arita, Yoshihiko; Wright, Ewan M.; Dholakia, Kishan (2015-02) - Journal article
    We experimentally create a 'perfect' vortex beam, which has a uniform ring profile and fixed radius. In contrast with other vortex fields, the intensity profile is independent of its topological charge. We then correct ...
  • Design and applications of flexible photonic membranes 

    Reader-Harris, Peter; Kirkpatrick, Blair C.; Di Falco, Andrea (SPIE, 2014-02-01) - Conference item
    In this paper we present the design and applications of flexible photonic membranes. We discuss their use as versatile photonic layers in the framework of lab-on-fibre applications, specifically focusing on the design of ...
  • How the lysine riboswitch folds 

    McCluskey, Kaley A. (University of St Andrews, 2015-08-28) - Thesis
    To respond to rapidly-changing stresses in their environment, bacterial cells must be able to sense a variety of chemical cues and respond to them by activating the relevant genes. The lysine riboswitch is a short RNA ...
  • Interference-free superposition of nonzero order light modes : Functionalized optical landscapes 

    Cizmar, Tomas; Dalgarno, Heather Isla Campbell; Ashok, Praveen Cheriyan; Gunn-Moore, Frank J; Dholakia, Kishan (2011-02) - Journal article
    In this paper, we utilize the incoherent superposition of nonzero order light modes. We show that this approach brings an additional degree of freedom to the generation of optical fields and notably the formation of ...
  • Optical micromanipulation using dispersion-compensated and phase-shaped ultrashort pulsed lasers 

    Shane, Janelle (University of St Andrews, 2009-11-30) - Thesis
    Ultrashort pulsed lasers offer high peak powers at low average powers, making them ideal for maximising the efficiency of nonlinear excitation. Their broad bandwidths make it possible to tailor the pulse's temporal profile ...
  • Optical sorting and manipulation of microscopic particles 

    Milne, Graham (University of St Andrews, 2007-06-25) - Thesis
    Over the last few decades, the use of light to control and manipulate microscopic particles has become widespread. These methods are enabling new areas of research to flourish across the physical and biological sciences. This ...
  • Optical trapping with "on-demand" two-photon luminescence using Cr:LiSAF laser with optically addressed saturable Bragg reflector 

    Savitski, Vasili G.; Metzger, N Klaus; Calvez, Stephane; Burns, David; Sibbett, Wilson; Brown, C Tom A (2012-03-26) - Journal article
    We demonstrate a diode-pumped Cr:LiSAF laser with controllable and reliable fast switching between its continuous-wave and mode-locked states of operation using an optically-addressed semiconductor Bragg reflector, permitting ...
  • Optical trapping: optical interferometric metrology and nanophotonics 

    Lee, Woei Ming (University of St Andrews, 2010-06-25) - Thesis
    The two main themes in this thesis are the implementation of interference methods with optically trapped particles for measurements of position and optical phase (optical interferometric metrology) and the optical manipulation ...
  • Photoporation and optical manipulation of plant and mammalian cells 

    Mitchell, Claire A. (University of St Andrews, 2015-06-24) - Thesis
    Optical cell manipulation allows precise and non-invasive exploration of mammalian cell function and physiology for medical applications. Plants, however, represent a vital component of the Earth’s ecosystem and the knowledge ...
  • Rotation of two trapped microparticles in vacuum : observation of optically mediated parametric resonances 

    Arita, Yoshihiko; Mazilu, Michael; Vettenburg, Tom; Wright, Ewan; Dholakia, Kishan (2015-10-15) - Journal article
    We demonstrate trapping and rotation of two mesoscopic particles in vacuum using a spatial-light-modulator-based approach to trap more than one particle, induce controlled rotation of individual particles, and mediate ...