Now showing items 1-2 of 2

  • Functional properties of motoneurons derived from mouse embryonic stem cells 

    Miles, Gareth Brian; Yohn, D C; Wichterle, H; Jessell, T M; Rafuse, V F; Brownstone, R M (2004-09-08) - Journal article
    The capacity of embryonic stem (ES) cells to form functional motoneurons (MNs) and appropriate connections with muscle was investigated in vitro. ES cells were obtained from a transgenic mouse line in which the gene for ...
  • The SMN protein is a key regulator of nuclear architecture in differentiating neuroblastoma cells 

    Clelland, Allyson K.; Kinnear, Nicholas P.; Oram, Lisa; Burza, Julie; Sleeman, Judith Elizabeth (2009-11) - Journal article
    The cell nucleus contains two closely related structures, Cajal bodies (CBs) and gems. CBs are the first site of accumulation of newly assembled splicing snRNPs (small nuclear ribonucleoproteins) following their import ...