Now showing items 1-2 of 2

  • The development of novel myosin inhibitors 

    Lawson, Christopher Peter Abiodun Tevi (University of St Andrews, 2011-06) - Thesis
    This thesis describes a structure activity relationship (SAR) study on the recently discovered small molecule tool blebbistatin (S)-21 with particular emphasis on the development of novel synthetic protocols suitable for ...
  • N-hydroxyguanidines and related compounds as nitric oxide donors 

    Kulczynska, Agnieszka (University of St Andrews, 2009) - Thesis
    The design of new, improved NO-donor drugs is an important pharmacological objective due to the biological importance of nitric oxide. N-Hydroxyguanidines represent a useful class of NO donors where the mechanism of ...