Now showing items 1-2 of 2

  • Behavioural phenotyping of mice with genetic alterations of the GABA[subscript A] receptor 

    Foister, Nicola (University of St Andrews, 2010-06-23) - Thesis
    GABA is the main inhibitory neurotransmitter of the central nervous system. GABA[subscript A]Rs are multimeric transmembrane receptors, which are composed of 5 subunits. It is known that there are 19 subunits that can make ...
  • First syntheses of fluoromuscimols 

    Abdul Manan, Mohd Abdul Fatah (University of St Andrews, 2017-06-21) - Thesis
    Chapter 1 provides a general introduction on the role of bioisosterism of fluorine aiming to improve the pharmacokinetics properties of lead compounds. GABAA receptors specifically, synaptic GABAA receptors, extrasynaptic ...