Now showing items 1-3 of 3

  • Developing novel single molecule analyses of the single-stranded DNA binding protein from Sulfolobus solfataricus 

    Morten, Michael J. (University of St Andrews, 2015) - Thesis
    Single-stranded DNA binding proteins (SSB) bind to single-stranded DNA (ssDNA) that is generated by molecular machines such as helicases and polymerases. SSBs play crucial roles in DNA translation, replication and repair ...
  • Fluorescence resonance energy transfer studies of protein interactions 

    Martin, Sarah Friede (University of St Andrews, 2008-06-24) - Thesis
    This thesis presents an investigation of fluorescence resonance energy transfer (FRET) as a reporting signal for protein-protein interactions. Quantitative optical assays to measure protein binding, conjugation and ...
  • How the lysine riboswitch folds 

    McCluskey, Kaley A. (University of St Andrews, 2015-08-28) - Thesis
    To respond to rapidly-changing stresses in their environment, bacterial cells must be able to sense a variety of chemical cues and respond to them by activating the relevant genes. The lysine riboswitch is a short RNA ...