Now showing items 1-4 of 4

  • The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode 

    Cotton, James A.; Lilley, Catherine J.; Jones, Laura M.; Kikuchi, Taisei; Reid, Adam J.; Thorpe, Peter; Tsai, Isheng J.; Beasley, Helen; Blok, Vivian; Cock, Peter J. A.; Eves-van den Akker, Sebastian; Holroyd, Nancy; Hunt, Martin; Mantelin, Sophie; Naghra, Hardeep; Pain, Arnab; Palomares-Rius, Juan E.; Zarowiecki, Magdalena; Berriman, Matthew; Jones, John T.; Urwin, Peter E. (2014-03-03) - Journal article
    Background: Globodera pallida is a devastating pathogen of potato crops, making it one of the most economically important plant parasitic nematodes. It is also an important model for the biology of cyst nematodes. Cyst ...
  • The multifunctional NS1 protein of influenza A viruses 

    Hale, Benjamin Geoffrey; Randall, Richard Edward; Ortin, J; Jackson, David (2008-10) - Journal article
    The non-structural (NS1) protein of influenza A viruses is a non-essential virulence factor that has multiple accessory functions during viral infection. In recent years, the major role ascribed to NS1 has been its inhibition ...
  • The regulation of type I interferon production by paramyxoviruses 

    Goodbourn, S; Randall, Richard Edward (2009-09) - Journal article
    Experimentally, paramyxoviruses are conventionally considered good inducers of type I interferons (IFN-alpha/beta), and have been used as agents in the commercial production of human IFN-alpha. However, in the last few ...
  • A transient homotypic interaction model for the influenza A virus NS1 protein effector domain 

    Kerry, Philip S.; Ayllon, Juan; Taylor, Margaret A.; Hass, Claudia; Lewis, Andrew; Garcia-Sastre, Adolfo; Randall, Richard E.; Hale, Benjamin G.; Russell, Rupert J. (2011-03-28) - Journal article
    Influenza A virus NS1 protein is a multifunctional virulence factor consisting of an RNA binding domain (RBD), a short linker, an effector domain (ED), and a C-terminal 'tail'. Although poorly understood, NS1 multimerization ...