Now showing items 1-3 of 3

  • Characterisation of proteins involved in CRISPR-mediated antiviral defence in Sulfolobus solfataricus 

    Kerou, Melina L. (University of St Andrews, 2012-06-20) - Thesis
    One of the most surprising realisations to emerge from metagenomics studies in the early ‘00s was that the population of viruses and phages in nature is about 10 times larger than the population of prokaryotic organisms. ...
  • Structural and functional studies of bacterial outer membrane proteins 

    Lou, Hubing (University of St Andrews, 2010-02) - Thesis
    This thesis studies two particular bacterial outer membrane proteins called OmpC and Wzi, focusing on their expression, purification, crystallization and X-ray structure determination. A series of four naturally occurring ...
  • Structural studies of CRISPR-associated proteins 

    Reeks, Judith (University of St Andrews, 2013-11-29) - Thesis
    Clustered regularly interspaced short palindromic repeats (CRISPRs) act to prevent viral infection and horizontal gene transfer in prokaryotes. The genomic CRISPR array contains short sequences (“spacers”) that are derived ...