Now showing items 1-4 of 4

    • 17ß-Estradiol protects against the effects of a high fat diet on cardiac glucose, lipid and nitric oxide metabolism in rats 

      Zafirovic, Sonja; Obradovic, Milan; Sudar-Milovanovic, Emina; Jovanovic, Aleksandra; Stanimirovic, Julijana; Stewart, Alan J.; Pitt, Samantha J.; Isenovic, Esma R. (2017-05-05) - Journal article
      The aim of this study was to investigate the in vivo effects of estradiol (E2) on myocardial metabolism and inducible nitric oxide synthase (iNOS) expression/activity in obese rats. Male Wistar rats were fed with a normal ...
    • Changes in cardiac Na+/K+-ATPase expression and activity in female rats fed a high fat diet 

      Jovanovic, Aleksandra; Obradovic, Milan; Sudar-Milovanovic, Emina; Stewart, Alan J.; Pitt, Samantha J.; Alvantic, Dragan; Aleksic, Ema; Isenovic, Esma R. (2017-12) - Journal article
      The aim of this study was to investigate whether the presence of endogenous estradiol alters the effects of a high-fat (HF) diet on activity/expression of the cardiac Na+/K+-ATPase, via PI3K/IRS and RhoA/ROCK signalling ...
    • A high fat diet induces sex-specific differences in hepatic lipid metabolism and nitrite/nitrate in rats 

      Stanimirovic, Julijana; Obradovic, Milan; Jovanovic, Aleksandra; Sudar-Milovanovic, Emina; Zafirovic, Sonja; Pitt, Samantha Jane; Stewart, Alan James; Isenovic, Esma R (2016-04-01) - Journal article
      Men and women differ substantially in regard to the severity of insulin resistance (IR) but the underlying mechanism(s) of how this occurs is poorly characterized. We investigated whether a high fat (HF) diet resulted in ...
    • Influence of a high-fat diet on cardiac iNOS in female rats 

      Jovanovic, Aleksandra; Sudar-Milovanovic, Emina; Obradovic, Milan; Pitt, Samantha Jane; Stewart, Alan James; Zafirovic, Sonja; Stanimirovic, Julijana; Radak, Djordje; Isenovic, Esma R. (2017) - Journal article
      Overexpression of inducible nitric oxide synthase (iNOS) is a key link between high-fat (HF) diet induced obesity and cardiovascular (CV) disease. Several studies have reported that oestradiol has cardioprotective effects ...