Now showing items 1-3 of 3

    • Burkholderia pseudomallei genome plasticity associated with genomic island variation 

      Tumapa, Sarinna; Holden, Matthew T. G.; Vesaratchavest, Mongkol; Wuthiekanun, Vanaporn; Limmathurotsakul, Direk; Chierakul, Wirongrong; Feil, Edward J.; Currie, Bart J.; Day, Nicholas P. J.; Nierman, William C.; Peacock, Sharon J. (2008-04-25) - Journal article
      Background: Burkholderia pseudomallei is a soil-dwelling saprophyte and the cause of melioidosis. Horizontal gene transfer contributes to the genetic diversity of this pathogen and may be an important determinant of virulence ...
    • Genome sequencing defines phylogeny and spread of methicillin-resistant Staphylococcus aureus in a high transmission setting 

      Tong, Steven Y C; Holden, Matthew T G; Nickerson, Emma K; Cooper, Ben S; Köser, Claudio U; Cori, Anne; Jombart, Thibaut; Cauchemez, Simon; Fraser, Christophe; Wuthiekanun, Vanaporn; Thaipadungpanit, Janjira; Hongsuwan, Maliwan; Day, Nicholas P; Limmathurotsakul, Direk; Parkhill, Julian; Peacock, Sharon J (2014-12-09) - Journal article
      Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial infection. Whole-genome sequencing of MRSA has been used to define phylogeny and transmission in well-resourced healthcare settings, yet the ...
    • Global and regional dissemination and evolution of Burkholderia pseudomallei 

      Chewapreecha, Claire; Holden, Matthew T. G.; Vehkala, Minna; Välimäki, Niko; Yang, Zhirong; Harris, Simon R.; Mather, Alison E.; Tuanyok, Apichai; De Smet, Birgit; Le Hello, Simon; Bizet, Chantal; Mayo, Mark; Wuthiekanun, Vanaporn; Limmathurotsakul, Direk; Phetsouvanh, Rattanaphone; Spratt, Brian G.; Corander, Jukka; Keim, Paul; Dougan, Gordon; Dance, David A. B.; Currie, Bart J.; Parkhill, Julian; Peacock, Sharon J. (2017-01-23) - Journal article
      The environmental bacterium Burkholderia pseudomallei causes an estimated 165,000 cases of human melioidosis per year worldwide and is also classified as a biothreat agent. We used whole genome sequences of 469 B. pseudomallei ...