Now showing items 1-2 of 2

    • A cluster of cholinergic premotor interneurons modulates mouse locomotor activity 

      Zagoraiou, L; Akay, T; Martin, J F; Brownstone, R M; Jessell, T M; Miles, Gareth Brian (2009-12-10) - Journal article
      Mammalian motor programs are controlled by networks of spinal interneurons that set the rhythm and intensity of motor neuron firing. Motor neurons have long been known to receive prominent “C bouton” cholinergic inputs ...
    • Functional properties of motoneurons derived from mouse embryonic stem cells 

      Miles, Gareth Brian; Yohn, D C; Wichterle, H; Jessell, T M; Rafuse, V F; Brownstone, R M (2004-09-08) - Journal article
      The capacity of embryonic stem (ES) cells to form functional motoneurons (MNs) and appropriate connections with muscle was investigated in vitro. ES cells were obtained from a transgenic mouse line in which the gene for ...