Now showing items 1-3 of 3

  • The Ess/Type VII secretion system of Staphylococcus aureus shows unexpected genetic diversity 

    Warne, Ben; Harkins, Catriona P; Harris, Simon R; Vatsiou, Alexandra; Stanley-Wall, Nicola; Parkhill, Julian; Peacock, Sharon J; Palmer, Tracy; Holden, Matthew T G (2016-03-13) - Journal article
    BACKGROUND: Type VII protein secretion (T7SS) is a specialised system for excreting extracellular proteins across bacterial cell membranes and has been associated with virulence in Staphylococcus aureus. The genetic diversity ...
  • Functional analysis of the EsaB component of the Staphylococcus aureus Type VII secretion system 

    Casabona, M Guillermina; Buchanan, Grant; Zoltner, Martin; Harkins, Catriona P; Holden, Matthew T G; Palmer, Tracy (2017-12-01) - Journal article
    Type VII secretion systems (T7SS) are found in many bacteria and secrete proteins involved in virulence and bacterial competition. In Staphylococcus aureus the small ubiquitin-like EsaB protein has been previously implicated ...
  • Haem-iron plays a key role in the regulation of the Ess/type VII secretion system of Staphylococcus aureus RN6390 

    Casabona, M Guillermina; Kneuper, Holger; Alferes de Lima, Daniela; Harkins, Catriona P; Zoltner, Martin; Hjerde, Erik; Holden, Matthew T. G.; Palmer, Tracy (2017-12-01) - Journal article
    The Staphylococcus aureus type VII protein secretion system (T7SS) plays important roles in virulence and intra-species competition. Here we show that the T7SS in strain RN6390 is activated by supplementing the growth ...