Now showing items 1-4 of 4

    • Comparative whole genome sequence analysis of the carcinogenic bacterial model pathogen Helicobacter felis 

      Arnold, Isabelle C.; Zigova, Zuzana; Holden, Matthew; Lawley, Trevor D.; Rad, Roland; Dougan, Gordon; Falkow, Stanley; Bentley, Stephen D.; Mueller, Anne (2011-01) - Journal article
      The gram-negative bacterium Helicobacter felis naturally colonizes the gastric mucosa of dogs and cats. Due to its ability to persistently infect laboratory mice, H. felis has been used extensively to experimentally model ...
    • The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081 

      Thomson, Nicholas R.; Howard, Sarah; Wren, Brendan W.; Holden, Matthew T. G.; Crossman, Lisa; Challis, Gregory L.; Churcher, Carol; Mungall, Karen; Brooks, Karen; Chillingworth, Tracey; Feltwell, Theresa; Abdellah, Zahra; Hauser, Heidi; Jagels, Kay; Maddison, Mark; Moule, Sharon; Sanders, Mandy; Whitehead, Sally; Quail, Michael A.; Dougan, Gordon; Parkhill, Julian; Prentice, Michael B. (2006-12) - Journal article
      The human enteropathogen, Yersinia enterocolitica, is a significant link in the range of Yersinia pathologies extending from mild gastroenteritis to bubonic plague. Comparison at the genomic level is a key step in our ...
    • Global and regional dissemination and evolution of Burkholderia pseudomallei 

      Chewapreecha, Claire; Holden, Matthew T. G.; Vehkala, Minna; Välimäki, Niko; Yang, Zhirong; Harris, Simon R.; Mather, Alison E.; Tuanyok, Apichai; De Smet, Birgit; Le Hello, Simon; Bizet, Chantal; Mayo, Mark; Wuthiekanun, Vanaporn; Limmathurotsakul, Direk; Phetsouvanh, Rattanaphone; Spratt, Brian G.; Corander, Jukka; Keim, Paul; Dougan, Gordon; Dance, David A. B.; Currie, Bart J.; Parkhill, Julian; Peacock, Sharon J. (2017-01-23) - Journal article
      The environmental bacterium Burkholderia pseudomallei causes an estimated 165,000 cases of human melioidosis per year worldwide and is also classified as a biothreat agent. We used whole genome sequences of 469 B. pseudomallei ...
    • Routine use of microbial whole genome sequencing in diagnostic and public health microbiology 

      Koeser, Claudio U.; Ellington, Matthew J.; Cartwright, Edward J. P.; Gillespie, Stephen H.; Brown, Nicholas M.; Farrington, Mark; Holden, Matthew T. G.; Dougan, Gordon; Bentley, Stephen D.; Parkhill, Julian; Peacock, Sharon J. (2012-08-02) - Journal item
      Whole genome sequencing (WGS) promises to be transformative for the practice of clinical microbiology, and the rapidly falling cost and turnaround time mean that this will become a viable technology in diagnostic and ...