Now showing items 1-4 of 4

  • Asymmetric isothiourea-catalysed formal [3+2] cycloadditions of ammonium enolates with oxaziridines 

    Smith, Siobhan Rose; Fallan, Charlene; Taylor, James Edward; McLennan, Ross Sinclair; Daniels, David Sydney Bernard; Morrill, Louis Christian; Slawin, Alexandra Martha Zoya; Smith, Andrew David (2015-07-13) - Journal article
    A highly enantioselective Lewis base-catalysed formal [3+2] cycloaddition of ammonium enolates and oxaziridines to give stereodefined oxazolidin-4-ones in high yield is described. Employing an enantioenriched oxaziridine ...
  • Exploring the scope of the isothiourea-mediated synthesis of dihydropyridinones 

    Yeh, Pei-Pei; Daniels, David Sydney Bernard; Fallan, Charlene; Gould, Eoin Rory; Simal Fernandez, Carmen; Taylor, James Edward; Slawin, Alexandra Martha Zoya; Smith, Andrew David (2015-02-21) - Journal article
    The exploration and expansion of the scope of the isothiourea-mediated synthesis of dihydropyridinones is presented. The use of ketimines derived from α,β-unsaturated γ-ketoesters as the Michael acceptor in a Michael ...
  • N- to C-sulfonyl photoisomerisation of dihydropyridinones : a synthetic and mechanistic study 

    Yeh, Pei-Pei; Taylor, James Edward; Stark, Daniel Graham; Daniels, David Sydney Bernard; Fallan, Charlene; Walton, John Christopher; Smith, Andrew David (2017-10-16) - Journal article
    The scope and limitations of a photoinitiated N- to C-sulfonyl migration process within a range of dihydropyridinones is assessed. This sulfonyl transfer proceeds without erosion of either diastereo- or enantiocontrol, and ...
  • A scalable, chromatography-free synthesis of benzotetramisole 

    Daniels, David Sydney Bernard; Smith, Siobhan Rose; Lebl, Tomas; Shapland, P.; Smith, Andrew David (2015-01) - Journal article
    The scalable, chromatography-free synthesis of the chiral isothiourea benzotetramisole (BTM) in two steps from commercially available materials is presented. A detailed procedure for the synthesis of both enantiomers and ...