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    • Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells 

      Meehan, James; Ward, Carol; Turnbull, Arran; Bukowski-Wills, Jimi; Finch, Andrew; Jarman, Edward J.; Xintaropoulou, Chrysi; Martinez-Perez, Carlos; Gray, Mark; Pearson, Matthew; Mullen, Peter; Supuran, Claudia T.; Carta, Fabrizio; Harrison, David James; Kunkler, Ian H.; Langdon, Simon (2017) - Journal article
      Hypoxic cancer cells exhibit resistance to many therapies. This study compared the therapeutic effect of targeting the pH regulatory proteins (CAIX, NHE1 and V-ATPase) that permit cancer cells to adapt to hypoxic conditions, ...