Synthesis of phosphonate and phostone analogues of ribose-1-phosphates
Abstract
The synthesis of phosphonate analogues of ribose-1-phosphate and 5-fluoro-5-deoxyribose-1-phosphate is described. Preparations of both the alpha- and beta-phosphonate anomers are reported for the ribose and 5-fluoro-5-deoxyribose series and a synthesis of the corresponding cyclic phostones of each alpha-ribose is also reported. These compounds have been prepared as tools to probe the details of fluorometabolism in S. cattleya.
Citation
Nasomjai , P , O'Hagan , D & Slawin , A M Z 2009 , ' Synthesis of phosphonate and phostone analogues of ribose-1-phosphates ' , Beilstein Journal of Organic Chemistry , vol. 5 , 37 . https://doi.org/10.3762/bjoc.5.37
Publication
Beilstein Journal of Organic Chemistry
Status
Peer reviewed
ISSN
1860-5397Type
Journal article
Rights
© 2009 Nasomjai et al; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (http://www.beilstein-journals.org/bjoc)
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