Synthesis and single crystal structures of substituted-1,3-selenazol-2-amines
Abstract
The synthesis and X-ray single crystal structures of a series of new 4-substituted-1,3-selenazol-2-amines is reported. The efficient preparation of 4-substituted-1,3-selenazol-2-amines was carried out by two-component cyclization of the selenoureas with equi-molar amounts of α-haloketones. The selenoureas were obtained from the reaction of Woollins’ reagent with cyanamides, followed by hydrolysis with water. All new compounds have been characterized by IR spectroscopy, multi-NMR (1H, 13C, 77Se) spectroscopy, accurate mass measurement and single crystal X-ray structure analysis.
Citation
Hua , G , Du , J , Slawin , A M Z & Woollins , J D 2016 , ' Synthesis and single crystal structures of substituted-1,3-selenazol-2-amines ' , Molecules , vol. 22 , no. 1 , 46 . https://doi.org/10.3390/molecules22010046
Publication
Molecules
Status
Peer reviewed
ISSN
1420-3049Type
Journal article
Rights
Copyright (c) 2016, the authors. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
Description
This article belongs to the Special Issue Celebrating Two Centuries of Research in Selenium Chemistry: State of the Art and New ProspectivesCollections
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